Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients
نویسندگان
چکیده
منابع مشابه
[Helicobacter pylori: focus on CagA and VacA major virulence factors].
After colonizing the human gastric mucosa, Helicobacter pylori can remain within the host for years and even decades, and is associated with several, highly significant gastric pathologies. In Mexico, the seroprevalence at 1 year of age is 20% and the estimated increment in seropositivity per year is 5% for children aged 1-10 years. More than 80% of adults are infected by the time they are 18-2...
متن کاملAnalysis of antimicrobial susceptibility and virulence factors in Helicobacter pylori clinical isolates
BACKGROUND In this study, we evaluated the prevalence of primary resistance of Brazilian H. pylori isolates to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone. In addition, the vacA, iceA, cagA and cagE genotypes of strains isolated from Brazilian patients were determined and associated with clinical data in an effort to correlate these four virulence markers and anti...
متن کاملبررسی شیوع VacA و CagA در بیماران مبتلا به اولسر پپتیک
Background and Objective: Helicobacter pylori (H. pylori) infection is one of the most common gastrointestinal infections worldwide. Infection with H. pylori strains may results in different pathological manifestation and increased oxidative stress lead to a strong inflammatory response in gastric mucosa. There is continuing interest in identifying H. pylori virulence factors that might p...
متن کاملHelicobacter pylori cagA Status, vacA Subtypes and Histopathologic Findings in Iranian Patients with chronic gastritis
Background and Objective: Helicobacter pylori has several strains with different degrees of virulence. The aim of this study was to detect two major important virulence factors, cagA/vacA genotypes, and to determine correlations among different cagA/vacA genotypes and histological features of chronic gastritis in Iranian patients. Methods: In this cross- sectional study, Gastric bi...
متن کاملMultiplex-PCR-Based Screening and Computational Modeling of Virulence Factors and T-Cell Mediated Immunity in Helicobacter pylori Infections for Accurate Clinical Diagnosis
The outcome of H. pylori infection is closely related with bacteria's virulence factors and host immune response. The association between T cells and H. pylori infection has been identified, but the effects of the nine major H. pylori specific virulence factors; cagA, vacA, oipA, babA, hpaA, napA, dupA, ureA, ureB on T cell response in H. pylori infected patients have not been fully elucidated....
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ژورنال
عنوان ژورنال: Journal of Venomous Animals and Toxins including Tropical Diseases
سال: 2014
ISSN: 1678-9199
DOI: 10.1186/1678-9199-20-1